Drug Uses

Use Protopic only to treat eczema that has been diagnosed by a doctor.

How Taken

Apply a thin layer of Protopic to all skin areas that your doctor has diagnosed as eczema. Try to cover the affected areas completely.

Warnings/Precautions

Avoid sunlight and sun lamps, tanning beds, and treatment with UVA or UVB light. If you need to be outdoors after applying Protopic, wear loose fitting clothing that protects the treated area from the sun. In addition, ask your doctor what other type of protection from the sun you should use.

Missed Dose

Apply Protopic as soon as you can remember.

Possible Side Effects

The most common side effects of Protopic are stinging, soreness, a burning feeling, or itching of the skin treated with Protopic. These side effects are usually mild to moderate and are most common during the first few days of treatment and typically lessen if your skin heals.

Storage

Store Protopic at room temperature (59E to 86EF). Never leave Protopic in your car in cold or hot weather. Make sure the cap on the tube is tightly closed. Keep Protopic out of the reach of children.

Overdose

An overdose with Protopic is highly unlikely to occur. Seek medical attention immediately if you suspect an overdose.

More Information

Do not use Protopic for a condition for which it was not prescribed. If you have any concerns about Protopic, ask your doctor. Your doctor or pharmacist can give you information about Protopic that was written for health care professionals.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Smokers' Skin Is More Wrinkled, Even In Areas Shielded From Sunlight Science Daily — In classic movies, cigarette smoking was used as shorthand to convey sultriness and beauty. In the real world, the connection between smoking and one's appearance -- as many studies have shown -- has more to do with premature signs of aging and less to do with glamour and refinement. A new study from the University of Michigan Health System adds another dimension to the link between cigarette smoking and skin damage. The study suggests that smoking may be associated with a higher degree of aging on areas of skin, such as that of the inside of the upper arm, that are not normally exposed to sunlight. "We examined non-facial skin that was protected from the sun, and found that the total number of packs of cigarettes smoked per day and the total years a person has smoked were linked with the amount of skin damage a person experienced," says Yolanda R. Helfrich, M.D., lead author and assistant professor of dermatology at the U-M Medical School. The researchers developed a photonumeric scale that can be easily reproduced by other medical institutions to measure the degree of aging on patients' skin. The nine-point scale used information from photographs of the inside-upper-arm skin of the 77 participants. Two medical residents and a medical student were asked to look at the photographs and assign a grade in which zero represented no fine wrinkling and eight represented severe fine wrinkling. The same three people reviewed photos of the participants one year later, and the scores were used to determine the level of increase in the skin damage. Researchers also collected data about the participants from interviews, such as their age, ethnicity, history of cigarette smoking, use of non-steroidal anti-inflammatory drugs, use of dietary or herbal supplements, sun exposure, sunscreen use, tanning bed use and, for women, how many children they had given birth to, hormone therapy use and oral contraceptive use. Among the people in the study who were current or former smokers, they had smoked an average of about 24 years. In all, among participants who were 45 years or older, the degree of skin aging was found to be significantly higher in smokers than nonsmokers. In the 45-65 age group, smokers had an average score on the photonumeric scale of more than two, while nonsmokers had an average score of less than one. In the 65 and older age group, smokers had an average score of about six, while nonsmokers had an average score of approximately four. In addition to Helfrich, authors were Abena Ofori, M.D.; Ted A. Hamilton, M.S.; Jennifer Lambert, M.S.; Anya King, M.P.H.; John J. Voorhees, M.D.; and senior author Sewon Kang, M.D., all of the U-M Department of Dermatology; and Le Yu, M.D., now with Cedars Sinai Medical Center in Los Angeles.

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