Drug Uses

Nexium is used to treat gastroesophageal reflux disease (GERD), a condition in which backward flow of acid from the stomach causes heartburn and injury of the esophagus (food pipe between the mouth and stomach). Nexium is used to treat the symptoms of GERD, allow the esophagus to heal, and prevent further damage to the esophagus. It is also used with other medications to prevent stomach ulcers. Nexium is in a class of medications called proton pump inhibitors. It works by decreasing the amount of acid made in the stomach.

How Taken

Nexium comes as a delayed-release (long-acting) capsule to take it orally. It is usually taken once a day at least one hour before a meal. To help you remember to take Nexium, take it around the same time every day. Swallow the capsules whole; do not split, chew, or crush them. If you cannot swallow the capsule, put one tablespoon of cool, soft applesauce in an empty bowl. Open one Nexium capsule and carefully sprinkle the pellets onto the applesauce. Mix the pellets with the applesauce, and swallow the entire tablespoonful of the applesauce and pellet mixture immediately. Do not chew the pellets in the applesauce. Do not save the pellets and applesauce for later use.

Warnings/Precautions

Before taking Nexium, tell your doctor if you have ever had any type of liver disease. You may not be able to take Nexium, or you may require a dosage adjustment or special monitoring. Nexium is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take Nexium without first talking to your doctor if you are pregnant. It is not known whether Nexium passes into breast milk. Do not take Nexium without first talking to your doctor if you are breast-feeding a baby. Serious and occasionally fatal hypersensitivity (anaphylactic) reactions have been reported in patients on penicillin therapy. These reactions are more apt to occur if you have a history of penicillin hypersensitivity and/or a history of sensitivity to multiple allergens. Pseudo membranous colitis has been reported with nearly all antibacterial agents, including clarithromycin and amoxicillin, and may range in severity from mild to life threatening. Therefore, it is important to consider this diagnosis in patients who present with diarrhea subsequent to the administration of antibacterial agents.

Missed Dose

Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication unless otherwise directed by your doctor.

Possible Side Effects

Nexium side effects that may go away during treatment include headache, constipation, cough, or diarrhea. If they continue or are bothersome, check with your doctor. Contact your doctor IMMEDIATELY if you experience throat pain, chest pain, severe stomach pain, or coffee-ground vomit. An allergic reaction to Nexium is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction to Nexium include rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.

Storage

Store at 25°C (77°F); excursions permitted to 15 - 30°C (59 - 86°F). Keep container tightly closed. Dispense in a tight container if the product package is subdivided.

Overdose

Seek emergency medical attention. Symptoms of Nexium overdose include drowsiness, shortness of breath, tremor, loss of coordination, and seizures.

More Information

Some medicines or medical conditions may interact with Nexium. Notify your pharmacist or doctor of all prescription and over-the-counter medicine that you are taking. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Heartburn: Hints on Dealing With the Discomfort What is heartburn? Despite its name, heartburn doesn't affect the heart. Heartburn is a burning feeling in the lower chest, along with a sour or bitter taste in the throat and mouth. It usually occurs after eating a big meal or while lying down. The feeling can last for a few minutes or a few hours. What causes heartburn? When you eat, food passes from your mouth down a tube (about 10 inches long in most people) called the esophagus. To enter the stomach, the food must pass through an opening between the esophagus and stomach. This opening acts like a gate to allow food to pass into the stomach. Usually, this opening closes as soon as food passes through. But if it doesn't close, acid from your stomach can get through the opening and into your esophagus. This is called reflux. Stomach acid can irritate the esophagus and cause heartburn. What is hiatal hernia? Hiatal hernia is a condition in which part of the stomach is pushed up through the diaphragm (the muscle wall between the stomach and chest) and into the chest. Sometimes this causes heartburn. Things that can make heartburn worse * Cigarette smoking * Coffee (both regular and decaffeinated) and other drinks that contain caffeine * Alcohol * Citrus fruits * Tomato products * Chocolate, mints or peppermints * Fatty foods or spicy foods (pizza, chili, curry) * Onions * Excess weight * Aspirin or ibuprofen (one brand name: Motrin) * Some other medicines (check with your doctor) Can heartburn be serious? If you only have heartburn now and then, it's probably not serious. However, if you have heartburn frequently, it can lead to esophagitis (an inflamed lining of the esophagus). If esophagitis becomes severe, your esophagus might narrow and you might have bleeding or trouble swallowing. If you get more than occasional heartburn, it may be a symptom of acid reflux disease, gastroesophageal reflux disease (GERD), an inflamed stomach lining (gastritis), hiatal hernia or peptic ulcer. Tips on preventing heartburn * Place 4- to 6-inch blocks under the legs at the head of your bed to raise it. * Try to eat at least 2 to 3 hours before lying down. If you take naps, try sleeping in a chair. * Lose weight if you're overweight. * Don't overeat. * Eat high-protein, low-fat meals. * Avoid tight clothes and tight belts. * Avoid foods and other things that give you heartburn. Will antacids take care of heartburn? Antacids neutralize the acid that your stomach makes. For most people, antacids that you can get without a prescription (over-the-counter) give fast, short-term relief. However, antacids can cause diarrhea or constipation. Look for antacids that contain both magnesium hydroxide and aluminum hydroxide. (One causes constipation while the other causes diarrhea so they counteract each other.) Some brands of antacids include Maalox, Mylanta and Riopan. Follow the directions on the package. What if my symptoms get worse? If lifestyle changes and antacids don't help your symptoms, talk with your doctor. Your doctor may want you to take medicine or schedule you for some tests. Tests might include x-rays to check for ulcers, a pH test to check for acid in the esophagus, or an endoscopy to check for other conditions. During an endoscopy, your doctor looks into your stomach through a long, thin tube which is inserted down your esophagus. Your doctor may also check for H. pylori, a bacteria that can cause ulcers. What about medicines for heartburn? Several kinds of medicine can be used to treat heartburn. H2 blockers (some brand names: Pepcid, Tagamet, Zantac) reduce the amount of acid your stomach makes. Several are available without a prescription. Other medicines, such as omeprazole (brand name: Prilosec) and lansoprazole (brand name: Prevacid), also reduce how much acid the stomach makes. Metoclopramide (brand name: Reglan) reduces acid reflux. To find out what medicine is right for you, talk with your doctor.

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