Drug Uses

Naprosyn is indicated for the treatment of rheumatoid arthritis, osteoarthritis, juvenile arthritis, ankylosing spondylitis, tendonitis and bursitis, and acute gout. It is also indicated in the relief of mild to moderate pain, and for the treatment of primary dysmenorrhea. Naprosyn Suspension is recommended for juvenile rheumatoid arthritis in order to obtain the maximum dosage flexibility based on the patient's weight.

How Taken

Naprosyn comes as a regular tablet, an extended-release tablet, and a liquid to take by mouth. It usually is taken twice a day for arthritis, every 8 hours for gout, and once a day (extended-release tablets) or every 6-8 hours (regular tablets) as needed for pain. Naprosyn may cause an upset stomach. Take Naprosyn with food or milk.

Warnings/Precautions

Before taking this medication, tell your doctor if you have an allergy to aspirin or any other NSAIDs, have an ulcer or bleeding in your stomach, drink more than three alcoholic beverages a day, have liver disease, Have kidney disease, have a coagulation (bleeding) disorder, have congestive heart failure, have fluid retention, have heart disease, or have high blood pressure. You may not be able to take Naprosyn or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above. Naprosyn is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Naprosyn should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take Naprosyn without first talking to your doctor if you are pregnant. Naprosyn passes into breast milk and may affect a nursing infant. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.

Missed Dose

If you are taking Naprosyn on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose. If you are taking Naprosyn as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

Possible Side Effects

Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous. If you experience any of the following serious side effects, stop taking Naprosyn and seek medical treatment or contact your doctor immediately: an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); muscle cramps, numbness, or tingling; ulcers (open sores) in the mouth; rapid weight gain (fluid retention); seizures; decreased hearing or ringing in the ears; yellowing of your skin or eyes (jaundice); or abdominal cramping, heartburn, or indigestion. Other, less serious side effects may be more likely to occur. Continue to take Naprosyn and talk to your doctor if you experience dizziness or headache; nausea, diarrhea, or constipation; depression; fatigue or weakness; dry mouth; or irregular menstrual periods. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Store Naprosyn suspension at room temperature; avoid excessive heat, above 40°C (104°F). Dispense in light-resistant container. Store Naprosyn tablets at room temperature and in well-closed containers; dispense in light-resistant container.

Overdose

Significant over dosage may be characterized by drowsiness, heartburn, indigestion, nausea or vomiting, seizures. If you ingest a large number of tablets or a large volume of suspension, accidentally or purposefully consult a doctor, an emergency room, or a poison control left for advice.

More Information

Avoid prolonged exposure to sunlight. Naprosyn may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable. Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, Naprosyn may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking Naprosyn if you drink more than 3 alcoholic beverages a day. Use caution when driving, operating machinery, or performing other hazardous activities. Naprosyn may cause dizziness. If you experience dizziness, avoid these activities. Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to Naprosyn. Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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Estrogen injections might help keep women's minds sharp as they age, a new study of female monkeys suggests. For the study, published in this week's online issue of the Proceedings of the National Academy of Sciences, researchers at Mount Sinai School of Medicine, in New York City, removed the ovaries of four distinct groups of female rhesus monkeys. One group included old monkeys that received estrogen; a second group included old monkeys that did not receive estrogen; and there were two other groups of young monkeys that either received or did not receive estrogen. Latest Womens Health News * Thyroid Test Won't Help Pregnant Mom, Baby * Single Embryo Transfer Cuts Multiples * FDA Fish Recommendations Challenged * Mom's Low Cholesterol Tied to Preemie Births * Bird Flu Virus Can Infect Fetus Removing the monkeys' ovaries induced menopause. The older monkeys had their ovaries removed around the time of perimenopause -- before the onset of full menopause. Estrogen treatment involved pure estradiol injections every 21 days. The researchers periodically tested the monkeys on a series of cognitive tasks over the course of more than two years. Older monkeys that were treated with estrogen performed almost as well as the younger monkeys on the mind-challenging tests, the researchers reported, while untreated older monkeys showed dramatic cognitive declines. Surprisingly, the younger monkeys performed equally well whether or not they were treated with estrogen. The study also found that the estrogen-treated monkeys showed brain changes associated with the prevention of cognitive decline. On the other hand, the older untreated monkeys showed no signs of these changes. The findings suggest that the debate over whether hormone replacement therapy is beneficial may not be over, according to study co-author John H. Morrison, dean of basic sciences and the graduate school of biological sciences at Mount Sinai. "There's been a great deal of confusion as to whether estrogen helps or harms postmenopausal women, and our findings tell us is that there is a very critical window of opportunity in which estrogen may be helpful," he said in a prepared statement. He noted that this critical window could be around the time of perimenopause, when estrogen may be able to protect the brain from cognitive decline. "Estrogen levels decline in old age, so the brain may need a certain amount of circulating estrogen to remain supple. Timing may be everything," Morrison said.

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