Drug Uses

Aciphex decreases the amount of acid produced in your stomach. Aciphex is used to treat ulcers, gastroesophageal reflux disease (GERD or heartburn), and other conditions involving excessive stomach acid production.

How Taken

Aciphex is available for oral administration as delayed-release, enteric-coated tablets. The recommended adult oral dose is one Aciphex 20 mg delayed-release tablet to be taken once daily for four to eight weeks. Take each dose with a full glass of water. Do not break, chew, or split the tablets. Swallow them whole. They are specially formulated to release slowly in your body.

Warnings/Precautions

Before taking Aciphex, tell your doctor if you are taking any of the following medicines: ketoconazole (Nizoral), ampicillin (Omnipen, Principen), iron (Feosol, Mol-Iron, Fergon, Femiron, others), digoxin (Lanoxin, Lanoxicaps), or cyclosporine (Sandimmune, Neoral). You may not be able to take Aciphex, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above. Drugs other than those listed here may also interact with Aciphex. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Missed Dose

If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.

Possible Side Effects

Serious side effects from Aciphex are rare. Stop taking Aciphex and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives) to Aciphex. Less serious side effects from Aciphex are also uncommon. Continue to take Aciphex and talk to your doctor if you experience headache; upset stomach or diarrhea; insomnia or nervousness; or a rash or itching. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Storage

Keep Aciphex out of the reach of children. Store Aciphex at room temperature (between 59°F and 86°F). Protect Aciphex from moisture.

Overdose

Symptoms of an Aciphex overdose are not known. Seek emergency medical attention.

More Information

There are no restrictions on food, beverages, or activity while taking Aciphex, unless otherwise directed by your doctor. Do not stop taking Aciphex even if you begin to feel better. Your symptoms may improve before your condition is fully treated.

Disclaimer

This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.

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An esophageal stricture is a gradual narrowing of the esophagus, which can lead to swallowing difficulties. The strictures are caused by scar tissue that builds up in the esophagus. When the lining of the esophagus is damaged, scarring develops. When scarring occurs, the lining of the esophagus becomes stiff. In time, as this scar tissue continues to build up, the esophagus begins to narrow in that area. The result then is swallowing difficulties. One of the conditions that can lead to esophageal strictures is gastroesophageal reflux disease. Excessive acid is refluxed from the stomach up into the esophagus. This causes an inflammation in the lower part of the esophagus. Scarring will result after repeated inflammatory injury and healing, re-injury and rehealing. This scarring will produce damaged tissue in the form of a ring that narrows the opening of the esophagus.

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